Glaucoma is the leading cause of irreversible blindness worldwide, affecting around 700,000 people in England alone. Its most insidious quality is that in most cases it causes no pain and no visual symptoms in the early stages — peripheral vision is lost gradually and the brain compensates so effectively that patients often do not notice until a substantial proportion of their visual field has gone.
What is glaucoma?
Glaucoma is a group of eye conditions characterised by progressive damage to the optic nerve — the cable of 1.2 million nerve fibres that transmits visual information from the eye to the brain. In most cases, this damage is related to raised intraocular pressure (IOP), though some patients develop glaucoma with IOP in the normal range (normal tension glaucoma).
The most common type — chronic open-angle glaucoma (COAG) — develops slowly over years. Acute angle-closure glaucoma is a sudden, painful emergency (see our red eye article). Other types include normal tension glaucoma, pseudoexfoliative glaucoma, and pigment dispersion syndrome.
Risk factors
- Age — risk increases significantly after 60
- Family history — first-degree relative with glaucoma approximately doubles your risk
- Elevated intraocular pressure
- African-Caribbean ethnicity — higher prevalence and often earlier onset
- High myopia (short-sightedness)
- Long-term steroid use (eye drops, oral, or inhaled)
- Diabetes and hypertension
How is glaucoma detected?
Glaucoma is most commonly detected at a routine optician visit. The key tests are:
- Intraocular pressure measurement (tonometry) — a raised IOP is a risk factor but not diagnostic alone.
- Optic nerve assessment — examination and photographs of the optic disc to look for characteristic changes (cupping, notching, haemorrhages).
- Visual field test (perimetry) — a computerised test of the peripheral visual field. Loss of peripheral field is the hallmark of glaucoma damage.
- OCT (optical coherence tomography) — high-resolution imaging of the retinal nerve fibre layer, detecting thinning before visual field loss occurs.
- Pachymetry — corneal thickness measurement, as thin corneas give falsely low IOP readings.
Treatment
Glaucoma cannot be reversed — damage already done to the optic nerve is permanent. Treatment aims to lower IOP to prevent or slow further damage.
- Eye drops — the first-line treatment. Prostaglandin analogues (latanoprost, bimatoprost) are most commonly used. Drops must be used every day, indefinitely.
- Laser trabeculoplasty (SLT) — a laser procedure that improves drainage of fluid from the eye. Often recommended as a first-line treatment instead of drops. Effective in many patients for 3–5 years.
- Surgery (trabeculectomy / tube implant) — for glaucoma not controlled by drops or laser. Creates a new drainage route for intraocular fluid. Highly effective but requires careful post-operative monitoring.
NHS screening and optician referral
In the UK, anyone over 40 with a first-degree relative (parent, sibling, child) with glaucoma is entitled to free NHS sight tests. If your optician suspects glaucoma, they will refer you to an NHS or private ophthalmology clinic for a comprehensive glaucoma assessment.
Frequently Asked Questions
Can glaucoma be cured?
Glaucoma cannot currently be cured, and damage already done to the optic nerve cannot be reversed. However, with early detection and consistent treatment to lower intraocular pressure, progression can be halted or slowed significantly, and most patients with glaucoma retain functional vision for life.
My eye pressure was raised at the optician. Do I have glaucoma?
Not necessarily. Raised IOP (ocular hypertension) is a risk factor for glaucoma but is not the same as a glaucoma diagnosis, which requires evidence of optic nerve damage or visual field loss. Around half of people with raised IOP never develop glaucoma. However, ocular hypertension does warrant monitoring and in higher-risk cases, treatment to lower pressure.
Can I drive with glaucoma?
It depends on the extent of visual field loss. DVLA regulations in the UK require drivers to meet minimum visual field and acuity standards. Patients with significant glaucoma should inform the DVLA and may be asked to undergo a formal driving visual field test. Your ophthalmologist can advise you on your specific situation.
Mr Mohamed Mohyudin
MBChB BSc MSc FRCOphth CCT — Consultant Ophthalmic Surgeon, Spire Elland Hospital, Yorkshire. GMC 7039600.
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